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South American <i>Plasmodium falciparum</i> isolates reveal new insights into the role of PfAAT1 in mediating resistance to Chloroquine

2026-07-16

Abstract excerpt

Antimalarial drug resistance remains one of the most significant challenges to global malaria control. The emergence of resistance to chloroquine, the first truly globally distributed antimalarial, has been extensively studied but is still not fully understood. While mutations in the Plasmodium falciparum chloroquine resistance transporter (PfCRT) primarily drive resistance, the phenotype is complex and multigeni...

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Literature Corpus work
9d378c59-8f5d-560f-bdf7-e56970c56654
DOI
10.64898/2026.07.15.738636
Open publication

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South American <i>Plasmodium falciparum</i> isolates reveal new insights into the role of PfAAT1 in mediating resistance to ChloroquineDOI 10.64898/2026.07.15.738636
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