Article

Identification of Genomic Loci Associated with Cellular Rhythms in Diversity Outbred Mice

2026-05-29

Abstract excerpt

Inter-individual variation in human molecular and behavioral circadian rhythms motivates genetic dissection in model systems with human-like diversity. We quantified cellular clock phenotypes from primary skin fibroblasts of several hundred Diversity Outbred (DO) mice-each carrying a unique mosaic of eight founder genomes-by longitudinal bioluminescence recordings of a Bmal1-luciferase reporter (LumiCycle). Canoni...

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Literature Corpus work: 9d0c9026-c8eb-5d7f-955d-2920a51ab521
DOI: 10.64898/2026.05.28.728467

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