Article
High-throughput sleep phenotyping produces robust and heritable traits in Diversity Outbred mice and their founder strains.
Sleep - 12 May 2020
Keenan Brendan T, Galante Raymond J, Lian Jie, Simecek Petr, Gatti Daniel M, Zhang Lin, Lim Diane C, Svenson Karen L, Churchill Gary A, Pack Allan I
Abstract excerpt
STUDY OBJECTIVES: This study describes high-throughput phenotyping strategies for sleep and circadian behavior in mice, including examinations of robustness, reliability, and heritability among Diversity Outbred (DO) mice and their eight founder strains. METHODS: We performed high-throughput sleep and circadian phenotyping in male mice from the DO population (n = 338) and their eight founder strains: A/J (n = 6),...
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