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Mapping the multidimensional geometric landscape of graded phenotypic variation and progression in neurodegenerative syndromes

2023-10-12

Abstract excerpt

Clinical variants of Alzheimer’s disease and frontotemporal lobar degeneration display a spectrum of cognitive-behavioural changes varying between individuals and over time. Understanding the landscape of these graded individual-/group-level longitudinal variations is critical for precise phenotyping; however, this remains challenging to model. Addressing this challenge, we leverage the National Alzheimer’s Coordi...

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Literature Corpus work
9cf3ccbb-9e6c-5a11-a3d1-280451412aea
DOI
10.1101/2023.10.11.23296861
Open publication

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Mapping the multidimensional geometric landscape of graded phenotypic variation and progression in neurodegenerative syndromesDOI 10.1101/2023.10.11.23296861
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