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Article

Redefining the multidimensional clinical phenotypes of frontotemporal lobar degeneration syndromes.

Brain : a journal of neurology - 1 May 2020

Murley Alexander G, Coyle-Gilchrist Ian, Rouse Matthew A, Jones P Simon, Li Win, Wiggins Julie, Lansdall Claire, Rodríguez Patricia Vázquez, Wilcox Alicia, Tsvetanov Kamen A, Patterson Karalyn, Lambon Ralph Matthew A, Rowe James B

Abstract excerpt

The syndromes caused by frontotemporal lobar degeneration have highly heterogeneous and overlapping clinical features. There has been great progress in the refinement of clinical diagnostic criteria in the past decade, but we propose that a better understanding of aetiology, pathophysiology and symptomatic treatments can arise from a transdiagnostic approach to clinical phenotype and brain morphometry. In a...

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PMID: 32438414
DOI: 10.1093/brain/awaa097
PMCID: PMC7241953

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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