Article
Time’s up: Using data-driven phenotype-severity metrics not time to map progression in the dementias
2026-01-30
Abstract excerpt
Temporal measures, such as time from diagnosis or symptom onset are often used to track disease severity in neurodegenerative diseases. Due to variations in symptom awareness, clinical presentation timing, diagnostic delays, and disease progression rates, these temporal proxies introduce substantial variance and bias, making it very difficult to map progression clearly and accurately, and to severity-match across...
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Identifiers and source
- Literature Corpus work
- 29468c0f-8eb7-5f20-aba5-d37f8bddbb6c
- DOI
- 10.64898/2026.01.28.26344700