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Article

A novel nucleoid-associated protein coordinates chromosome replication and chromosome partition.

Nucleic acids research - 6 Sept 2017

Taylor James A, Panis Gaël, Viollier Patrick H, Marczynski Gregory T

Abstract excerpt

We searched for regulators of chromosome replication in the cell cycle model Caulobacter crescentus and found a novel DNA-binding protein (GapR) that selectively aids the initiation of chromosome replication and the initial steps of chromosome partitioning. The protein binds the chromosome origin of replication (Cori) and has higher-affinity binding to mutated Cori-DNA that increases Cori-plasmid replication in...

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Identifiers

PMID: 28911105
DOI: 10.1093/nar/gkx596
PMCID: PMC5587793

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Source receipt: pubmed, retrieved 7 Sept 2026.

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