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The Cryptococcus neoformans Titan cell is an inducible and regulated morphotype underlying pathogenesis

18 May 2018

Abstract excerpt

Fungal cells change shape in response to environmental stimuli, and these morphogenic transitions drive pathogenesis and niche adaptation. For example, dimorphic fungi switch between yeast and hyphae in response to changing temperature. The basidiomycete Cryptococcus neoformans undergoes an unusual morphogenetic transition in the host lung from haploid yeast to large, highly polyploid cells termed Titan cells....

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PMID: 29775474
DOI: 10.1371/journal.ppat.1006978

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The Cryptococcus neoformans Titan cell is an inducible and regulated morphotype underlying pathogenesisPMID 29775474Read ↗

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