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The <i>Cryptococcus neoformans</i> titanide is a pathogenic morphotype that arises from typical yeast cells in response to host-relevant conditions

2026-01-17

Abstract excerpt

Fungal morphogenesis is a major driver of disease outcome. For the opportunistic fungal pathogen Cryptococcus neoformans, extreme morphological heterogeneity within the lung environment drives dissemination, immune evasion, and drug resistance. One such morphotype is the small, oval, titanide (2-3 µm). This poorly understood cell type is prevalent in lung histology and under in vitro conditions that mimic the ho...

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Identifiers and source

Literature Corpus work
f56617a2-7eb0-51c0-b78e-cc7286fc662e
DOI
10.64898/2026.01.16.699923
Open publication

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