Article

Metabolic Signatures of Immune Checkpoint Inhibitor Response in Gynecologic Cancers: Insights from Flux Balance Analysis

2025-01-16

Abstract excerpt

<h4>ABSTRACT</h4> Modifiers of immune checkpoint inhibitor (ICI) responses in cancer patients are complex and remain poorly characterized, especially in gynecologic cancers. In this study, we explored fluxomic biomarkers that differentiate responders from non-responders to ICIs in a series of 49 patients with gynecologic cancers, including ovarian, cervical, and endometrial cancers. By applying metabolic enzyme e...

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Literature Corpus work: 9cb207d6-186d-56f1-b3e2-836f75c029f0
DOI: 10.1101/2025.01.14.631240

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