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One-carbon metabolic reprogramming and its relationship with tumor-infiltrating lymphocytes and Immune checkpoint in Pancreatic cancer

2025-05-07

Abstract excerpt

<title>Abstract</title> <p><bold>BACKGROUND </bold>The role of oncogene-driven metabolic reprogramming in pancreatic cancer (PC) remains unclear. This study explored the interplay between one-carbon metabolism (OCM), driver genes, and the tumor microenvironment (TME) in PC. <bold>METHODS </bold>Targeted metabolomics analyzed 136 PC serum samples. Transcriptomic and OCM gene data from 930 PC patients were obtained...

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Literature Corpus work
00b812a4-5001-5256-b7d0-7e1c4044b136
DOI
10.21203/rs.3.rs-6404670/v1
Open publication

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One-carbon metabolic reprogramming and its relationship with tumor-infiltrating lymphocytes and Immune checkpoint in Pancreatic cancerDOI 10.21203/rs.3.rs-6404670/v1
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