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Article

Metabolic landscape of clear cell renal cell carcinoma and search for metabolites predictive of drug response

2024-04-19

Abstract excerpt

<title>Abstract</title> <p>Background. Clear cell renal cell carcinoma (ccRCC) commonly exhibits biallelic inactivation of <italic>VHL</italic> genes, profoundly impacting intracellular metabolic pathways and utilization of metabolic substrates. The aims of this study were to validate the metabolomic profile previously identified in ccRCC surgical specimens, to construct a metabolic classification in ccRCC, and...

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Literature Corpus work
334e4a0d-611a-584b-a9d1-2c039c6affb0
DOI
10.21203/rs.3.rs-4245290/v1
Open publication

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