Article

Reduced Glucose Sensation Can Increase the Fitness of <i>Saccharomyces cerevisiae</i> Lacking Mitochondrial DNA

2015-08-10

Abstract excerpt

Damage to the mitochondrial genome (mtDNA) can lead to diseases for which there are no clearly effective treatments. Since mitochondrial function and biogenesis are controlled by the nutrient environment of the cell, it is possible that perturbation of conserved, nutrient-sensing pathways may successfully treat mitochondrial disease. We found that restricting glucose or otherwise reducing the activity of the prote...

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Literature Corpus work: 9c8cbb39-2d77-5d2c-8b06-ebdd75855d93
DOI: 10.1101/024331

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