Article
The Gap1 general amino acid permease acts as an amino acid sensor for activation of protein kinase A targets in the yeast Saccharomyces cerevisiae.
Molecular microbiology - 1 Nov 2003
Donaton Monica C V, Holsbeeks Inge, Lagatie Ole, Van Zeebroeck Griet, Crauwels Marion, Winderickx Joris, Thevelein Johan M
Abstract excerpt
Addition of a nitrogen source to yeast (Saccharomyces cerevisiae) cells starved for nitrogen on a glucose-containing medium triggers activation of protein kinase A (PKA) targets through a pathway that requires for sustained activation both a fermentable carbon source and a complete growth medium (fermentable growth medium induced or FGM pathway). Trehalase is activated, trehalose and glycogen content as well as...
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