Article

Effect of culture conditions and induction strategies on production of human interleukin-6 by a recombinant Aspergillus nidulans strain

1996-03-01

Abstract excerpt

Studies were carried out on factors affecting production of human interleukin-6 (hIL-6) by a recombinant Aspergillus nidulans strain. The expression system included the glucoamylase gene of A. niger and the promoter of the alcA gene. Supplementation of a salts medium, containing fructose and threonine, with acid hydrolysed casein enhanced biomass and hIL-6 production. Addition of the non-metabolisable inducer, cyc...

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Literature Corpus work: 9c57488b-61bf-5384-b2fb-391ca50add8f
DOI: 10.1016/s0953-7562(96)80169-9

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