Article

Enhancing genotype-phenotype association with optimized machine learning and biological enrichment methods

2024-06-15

Abstract excerpt

Genome-wide association studies (GWAS) are surging again owing to newer high-quality T2T-CHM13 and human pangenome references. Conventional GWAS methods have several limitations, including high false negatives. Non-conventional machine learning-based methods are warranted for analyzing newly sequenced, albeit complex, genomic regions. We present a robust machine learning-based framework for feature selection and a...

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Literature Corpus work: 9c3a16a6-2ec3-513e-ab85-eaf524f51017
DOI: 10.1101/2024.06.14.24308920

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