Article
Inferring transmission bottleneck size from viral sequence data using a novel haplotype reconstruction method
2020-01-03
Abstract excerpt
The transmission bottleneck is defined as the number of viral particles transmitted from one host to another. Genome sequence data has been used to evaluate the size of the transmission bottleneck between humans infected with the influenza virus, however, the methods used to make these estimates have some limitations. Specifically, approaches using viral allele frequency data may not fully capture a process which...
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Identifiers and source
- Literature Corpus work
- 9c1cd1a1-cdac-5294-965f-bea364211feb
- DOI
- 10.1101/2020.01.03.891242