Article
Quantifying between-Host Transmission in Influenza Virus Infections.
Cold Spring Harbor perspectives in medicine - 3 Aug 2020
Johnson Katherine E E, Ghedin Elodie
Abstract excerpt
The error-prone replication and life cycle of influenza virus generate a diverse set of genetic variants. Transmission between hosts strictly limits both the number of virus particles and the genetic diversity of virus variants that reach a new host and establish an infection. This sharp reduction in the virus population at transmission--the transmission bottleneck--is significant to the evolution of influenza...
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