Article

SARS-CoV-2 papain-like protease activates nociceptors to drive sneeze and pain

2024-01-11

Abstract excerpt

SARS-CoV-2, the virus responsible for COVID-19, triggers symptoms such as sneezing, aches and pain. 1 These symptoms are mediated by a subset of sensory neurons, known as nociceptors, that detect noxious stimuli, densely innervate the airway epithelium, and interact with airway resident epithelial and immune cells. 2–6 However, the mechanisms by which viral infection activates these neurons to trigger pain and a...

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Literature Corpus work: 9c13e8f7-5990-5723-a092-7e573ff76d86
DOI: 10.1101/2024.01.10.575114

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