Article

Activation of a nerve injury transcriptional signature in airway-innervating sensory neurons after LPS induced lung inflammation

2019-06-13

Abstract excerpt

<h4>ABSTRACT</h4> The lungs, the immune and nervous systems functionally interact to respond to respiratory environmental exposures and infections. The lungs are innervated by vagal sensory neurons of the jugular and nodose ganglia, fused together in smaller mammals as the jugular-nodose complex (JNC). While the JNC shares properties with the other sensory ganglia, the trigeminal (TG) and dorsal root ganglia (DRG...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d7150e59-0d2c-52e7-82fa-d0dde66c0412
DOI: 10.1101/669374

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Activation of a nerve injury transcriptional signature in airway-innervating sensory neurons after LPS induced lung inflammationDOI 10.1101/669374Read

Molecular profiling of murine sensory neurons in the nodose and dorsal root ganglia labeled from the peritoneal cavitySemantic proximity Read

Distinct and common expression of receptors for inflammatory mediators in vagal nodose versus jugular capsaicin-sensitive/TRPV1-positive neurons detected by low input RNA sequencingSemantic proximity Read

Comprehensive sequencing of the lung neuroimmune landscape in response to asthmatic inductionSemantic proximity Read

Spatial transcriptomics of dorsal root ganglia identifies molecular signatures of human nociceptorsSemantic proximity Read

Single nucleus transcriptomic analysis of human dorsal root ganglion neuronsSemantic proximity Read

Single-nucleus transcriptomic analysis of human dorsal root ganglion neuronsSemantic proximity Read

Acute lung injury induces sustained neuroinflammation and dysfunction in the brainstem nucleus of the solitary tract of ratsSemantic proximity Read

Transcriptome profiling of dorsal root ganglia in a rat model of complex regional pain syndrome type-I reveals potential mechanisms involved in painSemantic proximity Read

Spatial transcriptomics reveals unique molecular fingerprints of human nociceptorsSemantic proximity Read

scRNA-sequencing reveals subtype-specific transcriptomic perturbations in DRG neurons of <i>Pirt-EGFPf</i> mice in neuropathic pain conditionSemantic proximity Read

Evidence for vagal sensory neural involvement in influenza pathogenesis and diseaseSemantic proximity Read

A novel method to sort and enrich sensory neuronsSemantic proximity Read