Article

Human IgE producing B cells have a unique transcriptional program and generate high affinity, allergen-specific antibodies

2018-05-22

Abstract excerpt

IgE antibodies provide defense against helminth infections, but can also cause life-threatening allergic reactions. Despite their importance to human health, these antibodies and the cells that produce them remain enigmatic due to their scarcity in humans; much of our knowledge of their properties is derived from model organisms. Here we describe the isolation of IgE producing B cells from the blood of individuals...

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Literature Corpus work: 9c0e3c1e-002f-5e49-b211-7ea388b91d11
DOI: 10.1101/327866

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