Article

Integrated single cell analysis of blood and cerebrospinal fluid leukocytes in multiple sclerosis

2018-08-29

Abstract excerpt

<h4>Summary</h4> Cerebrospinal fluid (CSF) protects the central nervous system (CNS) and analyzing CSF aids the diagnosis of CNS diseases, but our understanding of CSF leukocytes remains superficial. Here, we firstly provide a transcriptional map of single leukocytes in CSF compared to blood. Leukocyte composition and transcriptome were compartment-specific with CSF-enrichment of myeloid dendritic cells and a bo...

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Literature Corpus work: 9bf36315-84d1-581f-8b8a-3de7649a3621
DOI: 10.1101/403527

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