Article

Haploinsufficiency of<i>ITSN1</i>is associated with Parkinson’s disease

2024-07-27

Abstract excerpt

<h4>Background</h4> Despite its significant heritability, the genetic underpinnings of Parkinson disease (PD) remain incompletely understood, particularly the role of rare variants. Advances in population-scale sequencing now provide an unprecedented opportunity to uncover additional large-effect rare genetic risk factors and expand our understanding of disease mechanisms. <h4>Methods</h4> We leveraged whole-genom...

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Literature Corpus work: 643cb44e-95a6-5bc7-9850-41b401eebf5e
DOI: 10.1101/2024.07.25.24310988

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