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Article

Value of CYP3A5 genotyping on determining initial dosages of tacrolimus for Chinese renal transplant recipients.

Transplantation proceedings - 1 Nov 2010

Zhang J, Zhang X, Liu L, Tong W

Abstract excerpt

Optimal blood levels of tacrolimus in transplant recipients are critically important to preserve the allograft. Suboptimal doses of the immunosuppressant can result in allograft toxicity or rejection. In the present study, we determined CYP3A5 genotypes of patients and analyzed their medical documents in 2 successive periods. In the first period, a fixed initial dosage of 0.1 mg/kg was prescribed daily for 28...

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Identifiers

PMID: 21094797
DOI: 10.1016/j.transproceed.2010.06.028

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