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Bone-Targeted SPIONs Mimicking Exercise-Induced Mechanical Stimulation to Activate Mitophagy and Suppress Osteocyte Senescence for Senile Osteoporosis Therapy

2026-06-17

Abstract excerpt

<title>Abstract</title> <p> Senile osteoporosis (SOP) is a highly prevalent age-related skeletal disorder, yet current management remains suboptimal. Exercise therapy is widely recognized as an effective non-pharmacological strategy to prevent and attenuate SOP, but its clinical utility is constrained in older individuals, underscoring the need for a safe, controllable, exercise-mimetic approach with a defined m...

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Literature Corpus work
9b7516f9-e15e-5967-98a5-9054c4f046be
DOI
10.21203/rs.3.rs-9920339/v1
Open publication

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Bone-Targeted SPIONs Mimicking Exercise-Induced Mechanical Stimulation to Activate Mitophagy and Suppress Osteocyte Senescence for Senile Osteoporosis TherapyDOI 10.21203/rs.3.rs-9920339/v1
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