Article

Magnetic nanocomplexes coupled with an external magnetic field modulate macrophage phenotype – a non-invasive strategy for bone regeneration

2023-09-06

Abstract excerpt

Chronic inflammation is a major cause for the pathogenesis of musculoskeletal diseases such as fragility fracture, and nonunion. Studies have shown that modulating the immune phenotype of macrophages from proinflammatory to prohealing mode can heal recalcitrant bone defects. Current therapeutic strategies predominantly apply biochemical cues, which often lack target specificity and controlling their release kineti...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 78e07cdb-1783-5241-b434-627d0cfcc9e0
DOI: 10.1101/2023.09.02.556050

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Magnetic nanocomplexes coupled with an external magnetic field modulate macrophage phenotype – a non-invasive strategy for bone regenerationDOI 10.1101/2023.09.02.556050Read

Remotely Temporal Scheduled Macrophage Phenotypic Transition Enables Optimized Immunomodulatory Bone Regeneration.Semantic proximity Read

Temporal Control over Macrophage Phenotype and the Host Response via Magnetically Actuated Scaffolds.Semantic proximity Read

Magnetic Field Changes Macrophage Phenotype.Semantic proximity Read

Magnetic Stimulation Drives Macrophage Polarization in Cell to–Cell Communication with IL-1β Primed Tendon CellsSemantic proximity Read

Microneedles loaded with cerium-manganese oxide nanoparticles for targeting macrophages in the treatment of rheumatoid arthritisSemantic proximity Read

Biophysical regulation of macrophages in health and diseaseSemantic proximity Read

Macrophage phenotypes in tissue repair and the foreign body response: Implications for biomaterial-based regenerative medicine strategies.Semantic proximity Read

Activatable Nanoreporters for Real-Time Tracking of Macrophage Phenotypic States Associated with Disease Progression.Semantic proximity Read

Distinct matrix viscoelasticity in bone fracture hematoma steers macrophage polarizationSemantic proximity Read

Bone-Targeted SPIONs Mimicking Exercise-Induced Mechanical Stimulation to Activate Mitophagy and Suppress Osteocyte Senescence for Senile Osteoporosis TherapySemantic proximity Read

Advancements in Nanoceria for Immunotherapy ApplicationsSemantic proximity Read

The impact of biomaterial characteristics on macrophage phenotypes in tissue engineering: a reviewSemantic proximity Read