Article

Dominoes with interlocking consequences triggered by zinc: Involvement of microelement- stimulated MSC-derived small extracellular vesicles in senile osteogenesis and osteoclast dialogue

2023-07-14

Abstract excerpt

As societal aging intensifies, senile osteoporosis has become a global public health concern. Bone microdamage is mainly caused by processes such as enhancing osteoclast activity or reducing bone formation by osteoblast-lineage cells. Compared with young individuals, extracellular vesicles derived from senescent bone marrow mesenchymal stem cells(BMSCs) increase the transient differentiation of bone marrow monocyt...

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Literature Corpus work: bda0e657-2e4d-51db-afce-1987ce45e684
DOI: 10.21203/rs.3.rs-3156990/v1

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