Article

Functional and spinal neuropeptidomic alterations in a new rat surgical model of osteoarthritic pain: A pilot study

2017-01-06

Abstract excerpt

<h4>Background: </h4> Osteoarthritis is the leading cause of chronic joint pain, causing important productivity and economic losses. It is believed that peripheral and centralized sensitization play a role in the creation and maintenance of a chronic painful state. Different animal models have been employed for the investigation of pain mechanisms and evaluation of potential treatments, but none of them are ideal...

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Literature Corpus work: 9b613c61-38fb-53af-ba27-8ba4db4a478a
DOI: 10.7287/peerj.preprints.2704v1

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