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Article

Nociceptive phenotype alterations of dorsal root ganglia neurons innervating the subchondral bone in osteoarthritic rat knee joints.

Osteoarthritis and cartilage - 1 Sept 2016

Aso K, Izumi M, Sugimura N, Okanoue Y, Ushida T, Ikeuchi M

Abstract excerpt

OBJECTIVE: Subchondral bone plays a role in generating knee joint pain in osteoarthritis (OA). The objective of this study was to clarify nociceptive phenotype alterations of subchondral bone afferents of the distal femur in mono-iodoacetate (MIA)-induced OA rats. METHODS: OA was induced by intra-articular injection of MIA in rats. Two different retrograde tracers were separately injected into the knee joint...

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Source

Identifiers

PMID: 27085969
DOI: 10.1016/j.joca.2016.04.009

Genes

MIA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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