Article
Temporal Transcriptomics Identifies Isoform-specific Trans-regulation by Multiple lncRNAs in Human iPSCs
2026-05-14
Abstract excerpt
Some long non-coding RNAs (lncRNAs) are known to regulate gene expression. However, the underlying temporal dynamics of lncRNAs influencing gene and epigenetic regulation and mechanisms of lncRNA regulation in trans are less understood. To investigate this, we genetically engineered 17 doxycycline-inducible lncRNA transgenes for ectopic expression at the H11 safe harbor locus in human pluripotent stem cells (hiPSC...
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Identifiers and source
- Literature Corpus work
- 9b41f16c-4276-5b37-baff-9ea73018fa14
- DOI
- 10.64898/2026.05.13.724994
