Article
Determination of the human cardiomyocyte mRNA and miRNA differentiation network by fine-scale profiling.
Stem cells and development - 20 Jul 2012
Babiarz Joshua E, Ravon Morgane, Sridhar Sriram, Ravindran Palanikumar, Swanson Brad, Bitter Hans, Weiser Thomas, Chiao Eric, Certa Ulrich, Kolaja Kyle L
Abstract excerpt
To gain insight into the molecular regulation of human heart development, a detailed comparison of the mRNA and miRNA transcriptomes across differentiating human-induced pluripotent stem cell (hiPSC)-derived cardiomyocytes and biopsies from fetal, adult, and hypertensive human hearts was performed. Gene ontology analysis of the mRNA expression levels of the hiPSCs differentiating into cardiomyocytes revealed 3...
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