Article
Role of Filamin C in Muscle Cells.
Biochemistry. Biokhimiia - 1 Sept 2024
Goliusova Daria V, Sharikova Margarita Y, Lavrenteva Kristina A, Lebedeva Olga S, Muranova Lidia K, Gusev Nikolai B, Bogomazova Alexandra N, Lagarkova Maria A
Abstract excerpt
Filamin C (FLNC) is a member of a high-molecular weight protein family, which bind actin filaments in the cytoskeleton of various cells. In human genome FLNC is encoded by the FLNC gene located on chromosome 7 and is expressed predominantly in striated skeletal and cardiac muscle cells. Filamin C is involved in organization and stabilization of thin actin filaments three-dimensional network in sarcomeres, and is...
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