Article

An in-depth analysis of phosphorylated tau in amyotrophic lateral sclerosis post-mortem motor cortex and cerebrospinal fluid

2021-01-04

Abstract excerpt

Although the molecular mechanisms underlying amyotrophic lateral sclerosis (ALS) are not yet fully understood, recent studies have described alterations in tau protein in both sporadic and familial ALS. However, it is unclear whether alterations in tau contribute to ALS pathogenesis. Here, we leveraged the ALS Knowledge Portal and Project MinE data sets and identified specific genetic variants clustering within th...

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Literature Corpus work: 9ad0b54e-afe1-5de4-89ff-14ee143cd3d1
DOI: 10.1101/2020.12.30.20248944

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