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Article

Phosphorylated Tau as a Candidate Biomarker for Amyotrophic Lateral Sclerosis

3 Feb 2014

Abstract excerpt

IMPORTANCE: An increasingly varied clinical spectrum of cases with amyotrophic lateral sclerosis (ALS) has been identified, and objective criteria for clinical trial eligibility are necessary. OBJECTIVE: To develop a cerebrospinal fluid (CSF) biomarker sensitive and specific for the diagnosis of ALS. DESIGN, SETTING, AND PARTICIPANTS: A case-control study including 51 individuals with ALS and 23 individuals with...

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PMID: 24492862
DOI: 10.1001/jamaneurol.2013.6064

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