Article

Uncovering genetic variations in HTR2A and miRNAs drivers of breast cancer risk in African American women

2026-08-01

Abstract excerpt

Background/Objectives: Triple-negative breast cancer (TNBC) disproportionately affects African American (AA) women, yet the molecular mechanisms remain poorly understood. Emerging evidence suggests that microRNAs (miRNAs) may play a critical role in cancer progression. This study investigated the association of HTR2A genetic variants and miRNA dysregulation in AA women with breast cancer. Methods: A total of 417 A...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9a636931-c6e1-52da-8dfc-2ac6e0d988eb
DOI: 10.46439/breastcancer.6.037

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Uncovering genetic variations in HTR2A and miRNAs drivers of breast cancer risk in African American womenDOI 10.46439/breastcancer.6.037Read

Using genome and transcriptome data from African-ancestry female participants to identify putative breast cancer susceptibility genes.Semantic proximity Read

African ancestry and risk variants associated with triple-negative breast cancer susceptibility in African American women.Semantic proximity Read

Mutational landscape of triple-negative breast cancer in African American women.Semantic proximity Read

Impact of NR5A2 and RYR2 3'UTR polymorphisms on the risk of breast cancer in a Chinese Han population.Semantic proximity Read

A multi-stage genome-wide association study of uterine fibroids in African Americans.Semantic proximity Read

Vitamin D receptor polymorphisms and associated miRNAs in the development of breast cancer in African American women.Semantic proximity Read

A Comprehensive Meta-Analysis of Breast Cancer Gene ExpressionSemantic proximity Read

Single nucleotide variants in metastasis-related genes are associated with breast cancer risk, by lymph node involvement and estrogen receptor status, in women with European and African ancestry.Semantic proximity Read

Genome-wide association study identifies 25 known breast cancer susceptibility loci as risk factors for triple-negative breast cancer.Semantic proximity Read

MicroRNAs within Basal-Like Signature of Quadruple Negative Breast Cancer Impact Overall Survival in African AmericansSemantic proximity Read

Genetic variations in the Hippo signaling pathway and breast cancer risk in African American women in the AMBER Consortium.Semantic proximity Read

Unmutated RRAS2 emerges as a key oncogene in post-partum-associated triple negative breast cancer.Semantic proximity Read