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Article

Genetic variations in the Hippo signaling pathway and breast cancer risk in African American women in the AMBER Consortium.

Carcinogenesis - 1 Oct 2016

Zhang Jianmin, Yao Song, Hu Qiang, Zhu Qianqian, Liu Song, Lunetta Kathryn L, Haddad Stephen A, Yang Nuo, Shen He, Hong Chi-Chen, Sucheston-Campbell Lara, Ruiz-Narvaez Edward A, Bensen Jeannette T, Troester Melissa A, Bandera Elisa V, Rosenberg Lynn, Haiman Christopher A, Olshan Andrew F, Palmer Julie R, Ambrosone Christine B

Abstract excerpt

The Hippo signaling pathway regulates cellular proliferation and survival, thus exerting profound effects on normal cell fate and tumorigenesis. Dysfunction of the Hippo pathway components has been linked with breast cancer stem cell regulation, as well as breast tumor progression and metastasis. TAZ, a key component of the Hippo pathway, is highly expressed in triple negative breast cancer; however, the...

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Source

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Identifiers

PMID: 27485598
DOI: 10.1093/carcin/bgw077
PMCID: PMC5035397

Genes

CDH1
CDK1
PTPN14

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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