Article

MicroRNAs within Basal-Like Signature of Quadruple Negative Breast Cancer Impact Overall Survival in African Americans

2022-07-27

Abstract excerpt

<h4>Background: </h4> We previously found that QNBC tumors are more frequent in African Americans compared to TNBC tumors. To characterize this subtype further, we sought to determine the miRNA-mRNA profile in QNBC patients based on race. <h4>Methods:</h4> Both miRNA and mRNA expression data were analyzed from TCGA and validated using datasets from the METABRIC, TCGA proteomic, and survival analysis by KMPLOT. <h4...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 062ed623-adbe-5157-9a9c-ef512c23f185
DOI: 10.20944/preprints202207.0409.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

MicroRNAs within Basal-Like Signature of Quadruple Negative Breast Cancer Impact Overall Survival in African AmericansDOI 10.20944/preprints202207.0409.v1Read

A Panel of miRNAs as Prognostic Markers for African-American Patients with Triple Negative Breast CancerSemantic proximity Read

A Comprehensive Meta-Analysis of Breast Cancer Gene ExpressionSemantic proximity Read

Updated Biomarkers for TNBC in African vs. Caucasian American WomenSemantic proximity Read

Unravelling triple-negative breast cancer molecular heterogeneity using an integrative multiomic analysis.Semantic proximity Read

Triple Negative Breast Cancer Profile, from Gene to microRNA, in Relation to EthnicitySemantic proximity Read

Molecular profiling of a real-world breast cancer cohort with genetically inferred ancestries reveals actionable tumor biology differences between European ancestry and African ancestry patient populations.Semantic proximity Read

Basal-like breast cancer: molecular profiles, clinical features and survival outcomesSemantic proximity Read

Comparative analysis of triple-negative breast cancer transcriptomics of Kenyan, African American and Caucasian WomenSemantic proximity Read

Mutational landscape of triple-negative breast cancer in African American women.Semantic proximity Read

Differences in the mutational landscape of triple-negative breast cancer in African Americans and Caucasians.Semantic proximity Read

Age and ethnic-driven molecular and clinical disparity of East Asian breast cancersSemantic proximity Read

Exploration of prognostic value and underlying mechanism of P2RY14 in triple negative breast cancer by multi-omicsSemantic proximity Read