Article

Geometric Tumor Embolic Budding Characterizes Inflammatory Breast Cancer

2022-02-23

Abstract excerpt

<h4>Background: </h4> The sina qua non of IBC is numerous tumor emboli especially within dermal lymphatics. The explanation remains a mystery. Methods In observational human studies comparing IBC with non-IBC, although common tumor parameters such as Ki-67 index, mitotic count and nuclear size showed a reasonable overlap, there was a dramatic exponential or geometric difference in embolic density and a significan...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9a5cc27f-f6a8-59d7-81b8-4fe7afaf3139
DOI: 10.21203/rs.3.rs-1377051/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Geometric Tumor Embolic Budding Characterizes Inflammatory Breast CancerDOI 10.21203/rs.3.rs-1377051/v1Read

An intact overexpressed E-cadherin/alpha,beta-catenin axis characterizes the lymphovascular emboli of inflammatory breast carcinoma.Semantic proximity Read

Multiscale Modeling Uncovers Macrophage Infiltration and TNF-α Signaling Networks for Targeting in Inflammatory Breast Cancer Tumor EmboliSemantic proximity Read

Cooperative role of E-cadherin and sialyl-Lewis X/A-deficient MUC1 in the passive dissemination of tumor emboli in inflammatory breast carcinoma.Semantic proximity Read

The lymphovascular embolus of inflammatory breast cancer exhibits a Notch 3 addictionSemantic proximity Read

Tumor-derived FXII engages the intrinsic coagulation cascade to support breast cancer liver metastasisSemantic proximity Read

Tumor emboli-associated adaptive stress response signatures identify aggressive disease features in inflammatory breast cancerSemantic proximity Read

Inflammatory Breast Cancer: a model for investigating cluster-based disseminationSemantic proximity Read

Stabilization of E-cadherin adhesions by COX-2/GSK3β signaling is a targetable pathway in metastatic breast cancerSemantic proximity Read

Distinct Pathogenesis of Pancreatic Cancer Microvesicle–Associated Venous Thrombosis Identifies New Antithrombotic Targets In VivoSemantic proximity Read

Cell aggregation prevents anoikis and induces CD44 cleavage by maintaining lipid raft integrity to promote triple negative breast cancer metastasisSemantic proximity Read

Mitogen activated protein kinase pathway is involved in RhoC GTPase induced motility, invasion and angiogenesis in inflammatory breast cancer.Semantic proximity Read

To study the utility of tumor budding as a histopathological marker in comparison to various histopathological parameters and TNM staging in breast carcinomaSemantic proximity Read