Article

Deficiency of FRMD5 results in neurodevelopmental dysfunction and autistic-like behavior in mice

2023-08-07

Abstract excerpt

<title>Abstract</title> <p>Postsynaptic scaffolding proteins are causally associated with the pathophysiology of autism spectrum disorders (ASDs), a finding that is supported by several large-scale genomic studies 1,2 as well as in vitro and in vivo neurobiological studies of mutations in animal models 3,4. However, since ASD patients illustrate distinct phenotypic and genetic heterogeneity, each individual mutat...

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Literature Corpus work: 9a3eeb0b-debf-557d-a396-79faae5a0d6d
DOI: 10.21203/rs.3.rs-3202261/v1

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