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Article

Autism and the synapse: emerging mechanisms and mechanism-based therapies.

Current opinion in neurology - 1 Apr 2015

Ebrahimi-Fakhari Darius, Sahin Mustafa

Abstract excerpt

PURPOSE OF REVIEW: Recent studies have implicated hundreds of genetic variants in the cause of autism spectrum disorder (ASD). Genes involved in 'monogenic' forms of syndromic ASD converge on common pathways that are involved in synaptic development, plasticity and signaling. In this review, we discuss how these 'developmental synaptopathies' inform our understanding of the molecular disease in ASD and highlight...

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Identifiers

PMID: 25695134
DOI: 10.1097/WCO.0000000000000186

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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