Functional consequences of mutations in postsynaptic scaffolding proteins and relevance to psychiatric disorders.

Abstract excerpt

Functional studies on postsynaptic scaffolding proteins at excitatory synapses have revealed a plethora of important roles for synaptic structure and function. In addition, a convergence of recent in vivo functional evidence together with human genetics data strongly suggest that mutations in a variety of these postsynaptic scaffolding proteins may contribute to the etiology of diverse human psychiatric disorders...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cytoskeletal Proteins
• Share to Mental Disorders
• Share to Models, Neurological