Genome-Scale Codon Deoptimization Enables Attenuation of Rift Valley Fever Virus

Abstract excerpt

Rift Valley Fever Virus (RVFV) is a mosquito-borne zoonotic pathogen responsible for severe disease in domestic and wild ungulates as well as humans, representing a major threat to livestock production and human public health. RVFV is endemic in many African countries and has the potential to spread to new geographical regions. Current vaccines have limitations in safety and efficacy, highlighting the need for str...

Topics

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• Animal Virus Infections Studies
• Influenza Virus Research Studies
• Insect symbiosis and bacterial influences
• interferon and immune responses
• Mosquito-borne diseases and control
• Respiratory viral infections research
• RNA and protein synthesis mechanisms
• Viral gastroenteritis research and epidemiology

Identifiers and source

Literature Corpus work

9a3d5000-e024-58eb-8ad2-4af9b8180408

DOI

10.64898/2026.08.13.744589