Article
The distribution of the extrachromosomal DNA molecules in early lung cancer
2024-03-07
Abstract excerpt
<h4>Background: </h4> Lung cancer (LC) is a cancer with high mortality worldwide. Research on the distribution and nature of extrachromosomal DNA molecules (EcDNAm) in early LC is scarce. Methods After removing linear DNA and mitochondrial circular DNA, EcDNAm were extracted from two paired LC tissue samples and amplified using rolling circle amplification. High throughput extrachromosomal DNA or RNA sequencing a...
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Identifiers and source
- Literature Corpus work
- 9a39f093-2992-5a18-9253-1e65d1ae89bd
- DOI
- 10.21203/rs.3.rs-4010987/v1