Article

Anti-TNF-α mAb protects intestinal mucosal barrier integrity in the patients of Crohn’s disease via P38 MAPK/NF-κB p65-mediated expression of tight junction proteins

2022-06-23

Abstract excerpt

<h4>Objective: </h4> To explore the potential mechanism of anti-TNF mAb therapy in protecting mucosal barrier integrity in the patients of Crohn's disease. <h4>Methods: </h4> 382 patients with active Crohn's disease from January 2018 to October 2019 were recruited and treated with anti-TNF mAb therapy at the week 0,2,6, then every 8 weeks. The general clinical data were evaluated at the 14 th week and the intestin...

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Literature Corpus work: 9a2dfcd8-7355-5d37-bdd3-b206e6423c19
DOI: 10.21203/rs.3.rs-1769909/v1

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Anti-TNF-α mAb protects intestinal mucosal barrier integrity in the patients of Crohn’s disease via P38 MAPK/NF-κB p65-mediated expression of tight junction proteinsDOI 10.21203/rs.3.rs-1769909/v1Read

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