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Article

Clinical importance of IL-22 cascade in IBD.

Journal of gastroenterology - 1 Apr 2018

Mizoguchi Atsushi, Yano Arisa, Himuro Hidetomo, Ezaki Yui, Sadanaga Takayuki, Mizoguchi Emiko

Abstract excerpt

IL-22 is a relatively new cytokine that is characterized by several unique biological properties. In the intestines, the effect of IL-22 is restricted mainly to non-lymphoid cells such as epithelial cells. Interestingly, the expression pattern and major cellular source of IL-22 have distinct difference between large and small intestines. IL-22 possesses an ability to constitutively activate STAT3 for promoting...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29075900
DOI: 10.1007/s00535-017-1401-7
PMCID: PMC5866830

Genes

STAT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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