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IL-22 is increased in active Crohn’s disease and promotes proinflammatory gene expression and intestinal epithelial cell migration

2006-03-14

Abstract excerpt

IL-22 is produced by activated T cells and signals through a receptor complex consisting of IL-22R1 and IL-10R2. The aim of this study was to analyze IL-22 receptor expression, signal transduction, and specific biological functions of this cytokine system in intestinal epithelial cells (IEC). Expression studies were performed by RT-PCR. Signal transduction was analyzed by Western blot experiments, cell proliferati...

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Literature Corpus work
1f6ec2d3-f7a9-52ad-93a1-f5d20a406066
DOI
10.1152/ajpgi.00513.2005
Open publication

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IL-22 is increased in active Crohn’s disease and promotes proinflammatory gene expression and intestinal epithelial cell migrationDOI 10.1152/ajpgi.00513.2005
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