Article

The Role of TGF-β, Activin and Follistatin in Inflammatory Bowel Disease

2023-04-11

Abstract excerpt

Inflammatory bowel disease (IBD) is an immune-mediated inflammatory condition predominantly affecting the gastrointestinal (GI) tract. An increasing prevalence of IBD has been observed globally. The pathogenesis of IBD includes a complex interplay between the intestinal microbiome, diet, genetic factors and immune responses. The consequent imbalance of inflammatory mediators ultimately leads to intestinal mucosal...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0ad453e5-6be6-54b6-b612-6b5613d402d8
DOI: 10.3390/gidisord5020015

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The Role of TGF-β, Activin and Follistatin in Inflammatory Bowel DiseaseDOI 10.3390/gidisord5020015Read

Growth Factors in Inflammatory Bowel DiseaseSemantic proximity Read

Regulation of homeostasis and regeneration in the adult intestinal epithelium by the TGF ‐β superfamilySemantic proximity Read

Cellular and Molecular Therapeutic Targets in Inflammatory Bowel Disease—Focusing on Intestinal Barrier FunctionSemantic proximity Read

Immune cell-derived signals governing epithelial phenotypes in homeostasis and inflammation.Semantic proximity Read

Immunomodulators in inflammatory bowel disease: an emerging role for biologic agents.Semantic proximity Read

The NF-κB signaling system in the immunopathogenesis of inflammatory bowel diseaseSemantic proximity Read

Inflammatory bowel diseases: highlights from the United European Gastroenterology Week 2008.Semantic proximity Read

Immunopathogenesis of Crohn's disease.Semantic proximity Read

Anti-TNF-α mAb protects intestinal mucosal barrier integrity in the patients of Crohn’s disease via P38 MAPK/NF-κB p65-mediated expression of tight junction proteinsSemantic proximity Read

Modulatory Effects of IFN-γ and IL-22 on Inflammatory Signaling and Cellular Responses in Intestinal Epithelial CellsSemantic proximity Read

Advances in the pathogenesis and treatment of IBD.Semantic proximity Read

Role of Rho GTPases in inflammatory bowel diseaseSemantic proximity Read