Article
Exploring inflammatory and apoptotic signatures in distinct Crohn's disease phenotypes: Way towards molecular stratification of patients and targeted therapy.
Pathology, research and practice - 1 Jun 2020
Stankovic Biljana, Dragasevic Sanja, Klaassen Kristel, Kotur Nikola, Srzentic Drazilov Sanja, Zukic Branka, Sokic Milutinovic Aleksandra, Milovanovic Tamara, Lukic Snezana, Popovic Dragan, Pavlovic Sonja, Nikcevic Gordana
Abstract excerpt
BACKGROUND: Crohn's disease (CD) is chronic inflammatory bowel disease with different phenotypic characteristics influencing disease prognosis and therapeutic strategies. The aim of this pilot study was to analyze selected inflammatory and apoptotic markers in non-inflamed and inflamed samples of ileal mucosa of non-stricturing/non-penetrating (NS/NP) and stricturing (S) CD mucosal phenotypes in order to...
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