Article

Identification and Validation of New Molecular Subtypes within the Early and Late Mild Cognitive Impairment Stages of Alzheimer’s Disease

2023-04-07

Abstract excerpt

<h4>ABSTRACT</h4> Alzheimer’s disease (AD) is a heterogeneous neurodegenerative condition. This study identifies clinically relevant new molecular subtypes of the early and late mild cognitive impairment (EMCI and LMCI) stages of AD from 401 patients in the ADNI consortium. Metabolomics and peripheral blood mononuclear cell (PBMC) transcriptomics data are integrated using Similarity Network Fusion (SNF), resultin...

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Literature Corpus work: 99cc8d8d-97df-573d-87f3-4e0b7bb56862
DOI: 10.1101/2023.04.06.23288268

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