Article

Multi-‘Omic Integration via Similarity Network Fusion to Detect Molecular Subtypes of Aging

2022-11-17

Abstract excerpt

<h4>Background</h4> Molecular subtyping of brain tissue provides insights into the heterogeneity of common neurodegenerative conditions, such as Alzheimer’s disease (AD). However, existing subtyping studies have mostly focused on single data modalities and only those individuals with severe cognitive impairment. To address these gaps, we applied Similarity Network Fusion (SNF), a method capable of integrating mul...

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Literature Corpus work: b505b92e-ccd8-5a00-ba42-68a2dcc087c8
DOI: 10.1101/2022.11.16.516806

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